Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 8/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692034 | 0.88 | PTGER4 (0.46) | PTGER4AGTR1AGTR2TP53KMT2A | |
| SCHEMBL6017951 | 0.87 | PTGER4 (0.46) | PTGER4AGTR1AGTR2TP53KMT2A | |
| SCHEMBL6018899 | 0.87 | PTGER4 (0.46) | PTGER4AGTR1AGTR2TP53KMT2A | |
| SCHEMBL1626267 | 0.86 | PTGER4 (0.61) | PTGER4TP53MAPTLMNACYP2C9 | |
| SCHEMBL1625803 | 0.79 | PTGER4 (0.39) | PTGER4TP53MAPTPOLB | |
| SCHEMBL1625349 | 0.77 | PTGER4 (0.65) | PTGER4TP53MAPTLMNACYP2C9 | |
| SCHEMBL691760 | 0.76 | PTGER4 (0.75) | PTGER4AGTR1AGTR2TP53KMT2A | |
| SCHEMBL30114805 | 0.76 | PTGER4 (0.75) | PTGER4AGTR1AGTR2TP53KMT2A | |
| SCHEMBL691506 | 0.75 | PTGER4 (0.59) | PTGER4AGTR1AGTR2TP53KMT2A | |
| SCHEMBL30114829 | 0.75 | PTGER4 (0.59) | PTGER4AGTR1AGTR2TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1666480-A1 | Aryl or Heteroaryl Fused Imidazole Compounds as intermediates for Anti-Inflammatory And Analgesic Agents. | PFIZER PHARMACEUTICALS INC. (JP) | 2006-06-07 | — | — | EP | disclosed |