Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 2/20 | 0.44 |
| ▸ | GABRD | O14764 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.44 |
| ▸ | GABRE | P78334 | 2/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28750906 | 0.84 | CLCN2 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15535968 | 0.83 | GABRP (0.46) | AKR1C2AKR1C1GABRPGABRDGABRA1 | |
| SCHEMBL5899194 | 0.82 | GABRP (0.45) | AKR1C2AKR1C1GABRPGABRDGABRA1 | |
| SCHEMBL7521299 | 0.80 | PPARA (0.54) | PPARATYRKAT8BIDMCL1 | |
| SCHEMBL5270072 | 0.79 | PPARA (0.56) | PPARATYRKAT8BIDMCL1 | |
| SCHEMBL7568313 | 0.79 | BID (0.49) | AKR1C2AKR1C1GABRPGABRDGABRA1 | |
| SCHEMBL17625912 | 0.79 | PPARA (0.56) | PPARATYRKAT8BIDMCL1 | |
| SCHEMBL17625900 | 0.79 | PPARA (0.56) | PPARATYRKAT8BIDMCL1 | |
| SCHEMBL5272862 | 0.79 | PPARA (0.56) | PPARATYRKAT8BIDMCL1 | |
| SCHEMBL7642104 | 0.79 | TSHR (0.50) | AKR1C2AKR1C1GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1469827-A4 | POLYMORPHS OF SODIUM 4- (4-CHLORO-2-HYDROXYBENZOYL)AMINO BUTANOATE | EMISPHERE TECH INC (US) | 2006-08-16 | — | — | EP | disclosed |
| EP-1469827-A2 | POLYMORPHS OF SODIUM 4- (4-CHLORO-2-HYDROXYBENZOYL)AMINO BUTANOATE | Emisphere Technologies, Inc. (US) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003057650-A2 | POLYMORPHS OF SODIUM 4-[(4-CHLORO-2-HYDROXYBENZOYL)AMINO]BUTANOATE | EMISPHERE TECHNOLOGIES, INC. (US) | 2003-07-17 | — | — | WO | disclosed |