Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571374 | 0.68 | HDAC8 (0.50) | HDAC8IMPDH2DYRK1A | |
| SCHEMBL14994785 | 0.64 | DYRK1A (0.36) | HDAC8DYRK1A | |
| SCHEMBL6797712 | 0.63 | PPARA (0.35) | HDAC8DYRK1A | |
| SCHEMBL11036129 | 0.61 | HDAC8 (0.31) | HDAC8DYRK1A | |
| SCHEMBL17701204 | 0.58 | DYRK1A (0.41) | HDAC8DYRK1A | |
| SCHEMBL14320606 | 0.58 | APP (0.50) | IMPDH2DYRK1A | |
| SCHEMBL19721707 | 0.58 | DYRK1A (0.43) | HDAC8IMPDH2DYRK1A | |
| SCHEMBL5904803 | 0.58 | DYRK1A (0.37) | HDAC8IMPDH2DYRK1A | |
| SCHEMBL27636593 | 0.58 | DYRK1A (0.37) | HDAC8DYRK1A | |
| SCHEMBL18050291 | 0.58 | DYRK1A (0.33) | HDAC8IMPDH2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060189645-A1 | Novel 6-phenylphenantridines | ALTANA PHARMA AG (DE) | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189645-A1 | Novel 6-phenylphenantridines | PDE4B, PDE4A, PDE4D | HDAC8 1005/4885IMPDH2 977/4885DYRK1A 1537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.