Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1571002 | 0.90 | PDK2 (0.38) | PDK2PGRAKR1A1AKR1B1LMNA | |
| SCHEMBL1928893 | 0.90 | PDK2 (0.43) | PDK2PGRAKR1A1AKR1B1GAA | |
| SCHEMBL1809551 | 0.83 | PDK2 (0.46) | PDK2PGRAKR1A1AKR1B1L3MBTL1 | |
| SCHEMBL1928517 | 0.81 | PDK2 (0.33) | PDK2 | |
| SCHEMBL14422055 | 0.81 | PDK2 (0.33) | PDK2 | |
| SCHEMBL20100976 | 0.81 | PDK2 (0.33) | PDK2LMNAHPGDCES1 | |
| SCHEMBL26084831 | 0.81 | PDK2 (0.34) | PDK2AKR1A1AKR1B1 | |
| SCHEMBL20542581 | 0.79 | PDK2 (0.40) | PDK2PGRAKR1A1AKR1B1CCR5 | |
| SCHEMBL15820873 | 0.76 | PDK2 (0.38) | PDK2AKR1A1AKR1B1NPC1CES1 | |
| SCHEMBL1926884 | 0.76 | TGM2 (0.35) | PGRTSHRLMNAHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7138483-B2 | Monomers, conjugated polymers and electronic devices using such polymers | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-11-21 | — | — | US | disclosed |
| US-20040192871-A1 | Monomers, conjugated polymers and electronic devices using such polymers | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-09-30 | — | — | US | disclosed |
| WO-2004072123-A2 | MONOMERS, CONJUGATED POLYMERS AND ELECTRONIC DEVICES USING SUCH POLYMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-08-26 | — | — | WO | disclosed |