SCHEMBL6019482

SCHEMBL6019482

C[C@H](NC(=O)[C@H](CCCNC1CCCc2cccnc21)NC(=O)c1ccc(CNCc2ccccn2)c2ccccc12)c1cccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 9/20 0.50
HDAC1 Q13547 2/20 0.38
HDAC6 Q9UBN7 2/20 0.38
FNTA P49354 1/20 0.35
FNTB P49356 1/20 0.35
PGGT1B P53609 1/20 0.35
CTSL P07711 1/20 0.34
CTSS P25774 1/20 0.34
CTSK P43235 1/20 0.34
METAP2 P50579 2/20 0.33
METAP1 P53582 2/20 0.33
ADORA2A P29274 1/20 0.33
CASR P41180 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6018341 0.90 CXCR4 (0.38) CXCR4HDAC1HDAC6FNTAFNTB
SCHEMBL6018159 0.87 HDAC1 (0.41) CXCR4HDAC1HDAC6FNTAFNTB
SCHEMBL6018347 0.86 FOLH1 (0.37) CXCR4HDAC1HDAC6FNTAFNTB
SCHEMBL6990541 0.86 FOLH1 (0.37) CXCR4HDAC1HDAC6FNTAFNTB
SCHEMBL6018818 0.86 FOLH1 (0.37) CXCR4HDAC1HDAC6FNTAFNTB
SCHEMBL6018112 0.82 HDAC1 (0.44) CXCR4HDAC1HDAC6CTSLCTSS
SCHEMBL6018125 0.82 HDAC1 (0.40) CXCR4HDAC1HDAC6FNTAFNTB
SCHEMBL6019435 0.82 MMP2 (0.38) CXCR4HDAC1HDAC6
SCHEMBL6017976 0.82 CXCR4 (0.61) CXCR4FNTAFNTBPGGT1BMETAP2
SCHEMBL6018408 0.80 HDAC1 (0.38) CXCR4HDAC1HDAC6CTSLCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7098215-B2 Nitrogenous compounds and antiviral drugs containing the same KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 2006-08-29 US claimed