Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6018783 | 0.76 | — | — | |
| SCHEMBL12652864 | 0.72 | MAPT (0.38) | MAPTDPP4 | |
| SCHEMBL26498590 | 0.72 | — | — | |
| SCHEMBL6019489 | 0.71 | — | — | |
| SCHEMBL14104786 | 0.69 | MAPT (0.36) | MAPTDPP4 | |
| SCHEMBL6019364 | 0.69 | ALDH1A1 (0.44) | MAPT | |
| SCHEMBL6019260 | 0.69 | GBA1 (0.33) | — | |
| SCHEMBL18821171 | 0.69 | PIK3CD (0.52) | MAPTDPP4 | |
| SCHEMBL16472435 | 0.69 | PIK3CD (0.52) | MAPTDPP4 | |
| SCHEMBL9251617 | 0.69 | PIK3CD (0.52) | MAPTDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060228387-A1 | Dihydronepetalactams and N-substituted derivatives thereof | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060228387-A1 | Dihydronepetalactams and N-substituted derivatives thereof | NOTCH4, NRDC, BPHL | MAPT 635/4885DPP4 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.