Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145801 | 0.93 | MAOB (0.56) | MAOBHTR2ACYP3A4TRPA1ALDH1A1 | |
| SCHEMBL9861894 | 0.83 | HTR2A (0.41) | MAOBHTR2ACYP3A4TRPA1ALDH1A1 | |
| SCHEMBL2170349 | 0.79 | HTR2A (0.70) | MAOBHTR2AIDO1PAM | |
| SCHEMBL14037582 | 0.79 | HTR2A (0.70) | MAOBHTR2AIDO1PAM | |
| SCHEMBL107852 | 0.79 | HTR2A (0.70) | MAOBHTR2AIDO1PAM | |
| SCHEMBL107851 | 0.79 | HTR2A (0.70) | MAOBHTR2AIDO1PAM | |
| SCHEMBL831225 | 0.79 | HTR2A (0.76) | MAOBHTR2ACYP3A4TRPA1ALDH1A1 | |
| SCHEMBL28072917 | 0.76 | MAOB (0.52) | MAOBHTR2ACYP3A4TRPA1ALDH1A1 | |
| SCHEMBL27923443 | 0.75 | MAOB (0.47) | MAOBHTR2ACYP3A4TRPA1ALDH1A1 | |
| Styrene SCHEMBL812462 | 0.71 | HTR2A (0.59) | HTR2AALDH1A1IDO1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1356142-B1 | NON-POSTDRAWN POLYOLEFIN FIBERS WITH HIGH TENACITY | BOREALIS GMBH (AT) | 2006-04-19 | — | — | EP | disclosed |
| EP-1213375-A1 | Non-postdrawn polyolefin with high tenacity | Borealis GmbH (AT) | 2002-06-12 | — | — | EP | disclosed |