Styrene

Styrene

SCHEMBL812462

C=Cc1ccccc1.CC(C)CC=Cc1ccccc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.59
TSHR P16473 2/20 0.52
ALDH1A1 P00352 1/20 0.52
GRIK1 P39086 2/20 0.41
GRIK2 Q13002 2/20 0.41
IDO1 P14902 2/20 0.40
PAM P19021 1/20 0.40
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SIGMAR1 Q99720 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29242053 0.90 ALDH1A1 (0.46) HTR2ATSHRALDH1A1GRIK1GRIK2
SCHEMBL2170349 0.90 HTR2A (0.70) HTR2AGRIK1GRIK2IDO1PAM
SCHEMBL107852 0.90 HTR2A (0.70) HTR2AGRIK1GRIK2IDO1PAM
SCHEMBL107851 0.90 HTR2A (0.70) HTR2AGRIK1GRIK2IDO1PAM
Styrene SCHEMBL16875726 0.84 ALDH1A1 (0.50) HTR2ATSHRALDH1A1MEN1KMT2A
Styrene SCHEMBL7201521 0.82 ALDH1A1 (0.58) HTR2ATSHRALDH1A1MEN1KMT2A
Styrene SCHEMBL6325495 0.80 ALDH1A1 (0.45) HTR2ATSHRALDH1A1
SCHEMBL6435302 0.79 HTR2A (0.61) HTR2ATSHRALDH1A1GRIK1GRIK2
SCHEMBL6435300 0.79 HTR2A (0.61) HTR2ATSHRALDH1A1GRIK1GRIK2
SCHEMBL8826291 0.79 HTR2A (0.66) HTR2AGRIK1GRIK2IDO1PAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7661541-B2 Non-woven polymeric matrix for separation of leukocytes; continuous filament non-woven polymers made from biocompatible polymers BOSTON SCIENTIFIC SCIMED, INC. (US) 2010-02-16 US claimed
US-20060261005-A1 Non-woven polymeric matrix for separation of leukocytes; continuous filament non-woven polymers made from biocompatible polymers DAO KINH-LUAN LENNY D 2006-11-23 US claimed
US-7083697-B2 Non-woven polymeric matrix for separation of leukocytes BOSTON SCIENTIFIC SCIMED, INC. (US) 2006-08-01 US claimed
EP-1581273-A1 ENGINEERED SCAFFOLDS FOR PROMOTING GROWTH OF CELLS Boston Scientific Limited, an Irish company (BB) 2005-10-05 EP claimed
EP-1578590-A2 POROUS MELT SPUN POLYMERIC STRUCTURES AND METHOD OF MAKING THE SAME SciMed Life Systems, Inc. (US) 2005-09-28 EP claimed
WO-2004061177-A2 POROUS SPUN POLYMERIC STRUCTURES AND METHOD OF MAKING SAME SCIMED LIFE SYSTEMS, INC. (US) 2004-07-22 WO claimed
WO-2004060426-A1 ENGINEERED SCAFFOLDS FOR PROMOTING GROWTH OF CELLS BOSTON SCIENTIFIC LIMITED (BB) 2004-07-22 WO claimed
US-20040124146-A1 Non-woven polymeric matrix for separation of leukocytes SCIMED LIFE SYSTEMS, INC. 2004-07-01 US claimed
US-20040126405-A1 Engineered scaffolds for promoting growth of cells SCIMED LIFE SYSTEMS, INC. 2004-07-01 US claimed
CN-113893085-B Systems and methods for delivering multiple ocular implants 格劳科斯公司 2024-05-24 CN disclosed
US-11944573-B2 System and method for delivering multiple ocular implants GLAUKOS CORPORATION (US) 2024-04-02 US disclosed
US-11618874-B2 Methods for modulating osteochondral development using bioelectrical stimulation MEDRELIEF INC. (US) 2023-04-04 US disclosed
CN-113893085-A Systems and methods for delivering multiple ocular implants 格劳科斯公司 2022-01-07 CN disclosed
CN-110573117-B Systems and methods for delivering multiple ocular implants 格劳科斯公司 2021-10-26 CN disclosed
EP-1578590-A2 POROUS MELT SPUN POLYMERIC STRUCTURES AND METHOD OF MAKING THE SAME SciMed Life Systems, Inc. (US) 2005-09-28 EP disclosed
US-20050208093-A1 Phosphoryl choline coating compositions ABBOTT CARDIOVASCULAR SYSTEMS INC. 2005-09-22 US disclosed
WO-2004061177-A2 POROUS SPUN POLYMERIC STRUCTURES AND METHOD OF MAKING SAME SCIMED LIFE SYSTEMS, INC. (US) 2004-07-22 WO disclosed
WO-2004060426-A1 ENGINEERED SCAFFOLDS FOR PROMOTING GROWTH OF CELLS BOSTON SCIENTIFIC LIMITED (BB) 2004-07-22 WO disclosed
US-20040124146-A1 Non-woven polymeric matrix for separation of leukocytes SCIMED LIFE SYSTEMS, INC. 2004-07-01 US disclosed
US-20040126405-A1 Engineered scaffolds for promoting growth of cells SCIMED LIFE SYSTEMS, INC. 2004-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050208093-A1 Phosphoryl choline coating compositions PHOSPHO1, CHKA, SGMS1 HTR2A 1900/4885TSHR 3910/4885ALDH1A1 4693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.