SCHEMBL602012

SCHEMBL602012

C#CCC(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL23000816 0.85 CYP1A2 (0.31)
SCHEMBL19932832 0.72
SCHEMBL17600052 0.72
SCHEMBL14890672 0.72
SCHEMBL6141065 0.72
SCHEMBL9655193 0.68 LPAR1 (0.39)
SCHEMBL22750673 0.67
SCHEMBL24901083 0.67 ALDH1A1 (0.30)
SCHEMBL7900872 0.67 ALDH1A1 (0.33)
SCHEMBL6254594 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4204407-B1 PROCESS GIVAUDAN SA (CH) 2024-06-19 EP claimed
CN-106892936-A A kind of synthetic method of two grades of trifluoromethyl propargyl ethanols 合肥工业大学 2017-06-27 CN claimed
EP-2872502-B1 NOVEL INDAZOLES FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS INFECTION HOFFMANN LA ROCHE (CH) 2016-08-24 EP claimed
EP-2699578-B1 FLUOROALKYL-SUBSTITUTED PYRAZOLOPYRIDINES AND USE THEREOF BAYER IP GMBH (DE) 2016-04-20 EP claimed
EP-1768210-B1 Additives for overcharge protection in electrochemical cells AIR PROD & CHEM (US) 2015-04-29 EP claimed
EP-1979355-B1 SPIRO IMIDAZOLE DERIVATIVES AS PPAR MODULATORS IRM LLC (BM) 2010-08-18 EP claimed
EP-1201655-B1 Process for the preparation of non-steroidal glucocorticoid receptor modulators PFIZER PROD INC (US) 2005-09-07 EP claimed
EP-1334086-B1 PHENOXYPHENYL ALKANE SULFONATES BAYER HEALTHCARE AG (DE) 2005-04-06 EP claimed
US-20030120081-A1 Process for the preparation of non-steroidal glucocorticoid receptor modulators MURRY JERRY A (US) 2003-06-26 US claimed
US-6570020-B2 Reacting 2-(3,3,3-trifluoropropyl),2-hydroxy,4a-benzyl-7-carboxy-1,2,3,4,4a,9,10,10a -octahydrophenanthrene with 2-methyl-3-(aminomethyl)pyridine to form the corresponding pyridyl-substituted amide at position 7 PFIZER INC. 2003-05-27 US claimed
US-20020087005-A1 Process for the preparation of non-steroidal glucocorticoid receptor modulators MURRY JERRY A (US) 2002-07-04 US claimed
EP-1201655-A2 Process for the preparation of non-steroidal glucocorticoid receptor modulators Pfizer Products Inc. (US) 2002-05-02 EP claimed
CN-120058473-A 3-Alkyl-3-aryl-4, 4-trifluoro-1-butyne compound and preparation method thereof 南京工业大学 2025-05-30 CN disclosed
US-20250154409-A1 ETCHING METHOD RESONAC CORPORATION (JP) 2025-05-15 US disclosed
EP-4481795-A1 ETCHING METHOD Resonac Corporation (JP) 2024-12-25 EP disclosed
CN-118679553-A Etching method 株式会社力森诺科 2024-09-20 CN disclosed
US-6570020-B2 Reacting 2-(3,3,3-trifluoropropyl),2-hydroxy,4a-benzyl-7-carboxy-1,2,3,4,4a,9,10,10a -octahydrophenanthrene with 2-methyl-3-(aminomethyl)pyridine to form the corresponding pyridyl-substituted amide at position 7 PFIZER INC. 2003-05-27 US disclosed
US-20020087005-A1 Process for the preparation of non-steroidal glucocorticoid receptor modulators MURRY JERRY A (US) 2002-07-04 US disclosed
EP-1201655-A2 Process for the preparation of non-steroidal glucocorticoid receptor modulators Pfizer Products Inc. (US) 2002-05-02 EP disclosed
US-6369273-B1 ARYL ALCOHOLS OR ESTERS FOR ELEVATION OF PYRUVATE DHYDROGENASE ASTRAZENECA AB (SE) 2002-04-09 US disclosed