Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 18/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13711626 | 1.00 | MAOA (0.60) | MAOACYP3A4CYP2C9CYP2D6 | |
| Hydrochloric Acid SCHEMBL3369506 | 0.99 | MAOA (0.59) | MAOACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL13711526 | 0.94 | MAOA (0.60) | MAOACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL3368122 | 0.94 | MAOA (0.60) | MAOACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL13335031 | 0.94 | MAOA (0.59) | MAOACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL3367224 | 0.94 | MAOA (0.59) | MAOACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL3368245 | 0.93 | MAOA (0.63) | MAOACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL13711619 | 0.93 | MAOA (0.63) | MAOACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL3367256 | 0.93 | MAOA (0.64) | MAOACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL13711593 | 0.93 | MAOA (0.64) | MAOACYP3A4CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646629-A2 | CYCLOPROPYL GROUP SUBSTITUTED OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2006-04-19 | — | — | EP | claimed |
| WO-2005005398-A2 | CYCLOPROPYL GROUP SUBSTITUTED OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2005-01-20 | — | — | WO | claimed |
| EP-1646629-A2 | CYCLOPROPYL GROUP SUBSTITUTED OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005005398-A2 | CYCLOPROPYL GROUP SUBSTITUTED OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2005-01-20 | — | — | WO | disclosed |