Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 13/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | SGK1 | O00141 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | BLK | P51451 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6021793 | 1.00 | GRIN2B (0.41) | GRIN2BUSP30VCPSGK1ROCK2 | |
| SCHEMBL5477983 | 0.93 | GRIN2B (0.40) | GRIN2BUSP30VCP | |
| SCHEMBL5478744 | 0.93 | GRIN2B (0.40) | GRIN2BUSP30VCP | |
| SCHEMBL8292639 | 0.93 | GRIN2B (0.40) | GRIN2BUSP30VCP | |
| SCHEMBL5476896 | 0.90 | GRIN2B (0.40) | GRIN2BUSP30VCP | |
| SCHEMBL5480629 | 0.90 | GRIN2B (0.40) | GRIN2BUSP30VCP | |
| SCHEMBL5478765 | 0.89 | GRIN2B (0.42) | GRIN2BCCNA2CDK2 | |
| SCHEMBL5478767 | 0.89 | GRIN2B (0.42) | GRIN2BCCNA2CDK2 | |
| SCHEMBL14431024 | 0.89 | GRIN2B (0.42) | GRIN2BCCNA2CDK2 | |
| SCHEMBL5481000 | 0.86 | HRH4 (0.40) | USP30VCPSGK1ROCK2RPS6KA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668004-A1 | BENZOXAZOLE ACETONITRILES | Applied Research Systems ARS Holding N.V. (AN) | 2006-06-14 | — | — | EP | claimed |
| WO-2005026159-A1 | BENZOXAZOLE ACETONITRILES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-03-24 | — | — | WO | claimed |