Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 13/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5478765 | 1.00 | GRIN2B (0.42) | GRIN2BKDM4EPKMGPR119PRMT5 | |
| SCHEMBL5478767 | 1.00 | GRIN2B (0.42) | GRIN2BKDM4EPKMGPR119PRMT5 | |
| SCHEMBL8294105 | 0.91 | GRIN2B (0.35) | GRIN2BPRMT5CCNA2CDK2 | |
| SCHEMBL5478744 | 0.89 | GRIN2B (0.40) | GRIN2B | |
| SCHEMBL5477983 | 0.89 | GRIN2B (0.40) | GRIN2B | |
| SCHEMBL8292639 | 0.89 | GRIN2B (0.40) | GRIN2B | |
| SCHEMBL6021793 | 0.89 | GRIN2B (0.41) | GRIN2BCCNA2CDK2 | |
| SCHEMBL6021795 | 0.89 | GRIN2B (0.41) | GRIN2BCCNA2CDK2 | |
| SCHEMBL5477801 | 0.87 | GRIN2B (0.41) | GRIN2BKDM4EPKMGPR119PRMT5 | |
| SCHEMBL14431020 | 0.87 | GRIN2B (0.41) | GRIN2BKDM4EPKMGPR119PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185104-A1 | Benzoxazole acetonitriles | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2007-08-09 | — | — | US | disclosed |
| US-20070185104-A1 | Benzoxazole acetonitriles | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185104-A1 | Benzoxazole acetonitriles | PKD1, PC, GPR119 | GRIN2B 2653/4885KDM4E 2717/4885PKM 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.