Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4968223 | 0.89 | MAPK9 (0.45) | MAPK9MAPK10MEN1KMT2AMGLL | |
| SCHEMBL3480198 | 0.88 | MAPK9 (0.54) | MAPK9MAPK10MEN1KMT2AMGLL | |
| SCHEMBL2421128 | 0.87 | MAPK9 (0.55) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL3480236 | 0.77 | MAPK9 (0.57) | MAPK9MAPK10MEN1KMT2AMGLL | |
| SCHEMBL2421336 | 0.77 | MAPK9 (0.55) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL2422619 | 0.77 | MAPK9 (0.52) | MAPK9MAPK10MEN1KMT2AMGLL | |
| SCHEMBL7441861 | 0.76 | MAPK9 (0.48) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL2418948 | 0.76 | MAPK9 (0.59) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL2420177 | 0.76 | MAPK9 (0.60) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL27552252 | 0.75 | MGLL (0.46) | MAPK9MAPK10MGLLMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663193-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DIABETES | Applied Research Systems ARS Holding N.V. (AN) | 2006-06-07 | — | — | EP | claimed |
| WO-2005025558-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DIABETES | APPLIED RESERACH SYSTEMS ARS HOLDING N.V. (AN) | 2005-03-24 | — | — | WO | claimed |