⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456612 | 0.65 | — | — | |
| SCHEMBL12487280 | 0.65 | — | — | |
| SCHEMBL27313745 | 0.62 | — | — | |
| SCHEMBL28085398 | 0.62 | — | — | |
| SCHEMBL9862715 | 0.62 | — | — | |
| SCHEMBL592983 | 0.62 | — | — | |
| Ammonia Solution, Strong SCHEMBL28104395 | 0.62 | — | — | |
| SCHEMBL7115244 | 0.61 | — | — | |
| SCHEMBL11876827 | 0.61 | — | — | |
| SCHEMBL16556503 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613646-A2 | PROCESS FOR PREPARATION OF CYCLOSPORIN \"A\" ANALOGUES HAVING A TERMINAL DIENE GROUP | Isotechnika Inc. (CA) | 2006-01-11 | — | — | EP | claimed |
| US-20040220091-A1 | Process for preparation of cyclosporin A analogs | ISOTECHNIKA INC. (CA) | 2004-11-04 | — | — | US | claimed |
| WO-2004089960-A2 | PROCESS FOR PREPARATION OF CYCLOSPORIN “A” ANALOGUES HAVING A TERMINAL DIENE GROUP | ISOTECHNIKA INC. (CA) | 2004-10-21 | — | — | WO | claimed |
| EP-1732534-A1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | Applied Research Systems ARS Holding N.V. (AN) | 2006-12-20 | — | — | EP | disclosed |
| EP-1613646-A2 | PROCESS FOR PREPARATION OF CYCLOSPORIN \"A\" ANALOGUES HAVING A TERMINAL DIENE GROUP | Isotechnika Inc. (CA) | 2006-01-11 | — | — | EP | disclosed |
| WO-2005082347-A1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | APLLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-09-09 | — | — | WO | disclosed |
| US-20040220091-A1 | Process for preparation of cyclosporin A analogs | ISOTECHNIKA INC. (CA) | 2004-11-04 | — | — | US | disclosed |
| WO-2004089960-A2 | PROCESS FOR PREPARATION OF CYCLOSPORIN “A” ANALOGUES HAVING A TERMINAL DIENE GROUP | ISOTECHNIKA INC. (CA) | 2004-10-21 | — | — | WO | disclosed |
| EP-0800525-B1 | PROCESS FOR PREPARING TRIMETHYLSILYLOXY FUNCTIONALIZED ALKYLLITHIUM COMPOUNDS | FMC CORP (US) | 2003-04-09 | — | — | EP | disclosed |
| US-3983144-A | Novel 11β-alkyl steroids of the estrane series | AKZONA INCORPORATED (US) | 1976-09-28 | — | — | US | disclosed |