Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 2/20 | 0.44 |
| ▸ | TGM2 | P21980 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6436596 | 0.86 | LMNA (0.40) | USP5TGM2KDM4EMAPK9MAPK10 | |
| SCHEMBL6021792 | 0.82 | MAPK9 (0.45) | USP5TGM2KDM4EMAPK9MAPK10 | |
| SCHEMBL1518791 | 0.81 | MAPK9 (0.64) | USP5TGM2MAPK9MAPK10ALDH1A1 | |
| SCHEMBL2422985 | 0.79 | MAPK9 (0.46) | USP5TGM2KDM4EMAPK9MAPK10 | |
| SCHEMBL6431692 | 0.77 | MEN1 (0.62) | USP5TGM2MAPK9MAPK10ALDH1A1 | |
| SCHEMBL1518918 | 0.76 | MAPK9 (0.62) | USP5TGM2KDM4EMAPK9MAPK10 | |
| SCHEMBL2427220 | 0.74 | MAPK9 (0.58) | USP5TGM2MAPK9MAPK10MEN1 | |
| SCHEMBL2426728 | 0.74 | MAPK9 (0.58) | USP5TGM2KDM4EMAPK9MAPK10 | |
| SCHEMBL2427650 | 0.74 | KDM4E (0.47) | USP5TGM2KDM4EMAPK9MAPK10 | |
| SCHEMBL2422037 | 0.73 | MAPK9 (0.59) | USP5TGM2KDM4EMAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663193-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DIABETES | Applied Research Systems ARS Holding N.V. (AN) | 2006-06-07 | — | — | EP | claimed |
| WO-2005025558-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DIABETES | APPLIED RESERACH SYSTEMS ARS HOLDING N.V. (AN) | 2005-03-24 | — | — | WO | claimed |