Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5458474 | 0.73 | PPARD (0.48) | TRPV1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL27787498 | 0.72 | TRPV1 (0.44) | TRPV1MEN1KMT2ACASP3SIRT2 | |
| SCHEMBL5016811 | 0.71 | PTPN1 (0.34) | LMNAKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL18490110 | 0.71 | MAPT (0.33) | MEN1KMT2AKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL3230809 | 0.70 | GAA (0.46) | SMN1; SMN2 | |
| SCHEMBL16318892 | 0.70 | PPARD (0.41) | — | |
| SCHEMBL1600324 | 0.68 | IDO1 (0.41) | TACR1 | |
| SCHEMBL5438421 | 0.67 | GSTP1 (0.37) | TRPV1MEN1KMT2ALMNATHRB | |
| SCHEMBL16319093 | 0.67 | L3MBTL1 (0.65) | MEN1KMT2ALMNACASP3KDM4E | |
| SCHEMBL766830 | 0.67 | TRPV1 (0.55) | TRPV1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1690538-A1 | ISOXAZOLE DERIVATIVE HAVING AGONISTIC ACTIVITY AGAINST PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | SHIONOGI & CO., LTD. (JP) | 2006-08-16 | — | — | EP | disclosed |