Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 16/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761619 | 0.89 | AR (0.42) | PKMARPOLB | |
| SCHEMBL6023175 | 0.84 | KMT2A (0.52) | PKMPOLBGAAMEN1KMT2A | |
| SCHEMBL6023623 | 0.84 | PKM (0.70) | PKMARPOLBGAA | |
| SCHEMBL6022415 | 0.82 | PKM (0.47) | PKMARPOLBGAAMEN1 | |
| SCHEMBL6023053 | 0.82 | POLB (0.52) | PKMARPOLB | |
| SCHEMBL6022312 | 0.80 | POLB (0.48) | PKMARPOLBTP53KMT2A | |
| SCHEMBL6023629 | 0.80 | PKM (0.57) | PKMARPOLBGAA | |
| SCHEMBL6023494 | 0.79 | PKM (0.54) | PKMARPOLBTP53GAA | |
| SCHEMBL6023759 | 0.78 | POLB (0.65) | PKMARPOLBGAAMEN1 | |
| SCHEMBL6022319 | 0.78 | PKM (0.45) | PKMARPOLBTP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009052-B2 | Sulfonamide derivatives | WARNER LAMBERT COMPANY LLC (US) | 2006-03-07 | — | — | US | disclosed |