Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.57 |
| ▸ | PARG | Q86W56 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 12/20 | 0.45 |
| ▸ | PGR | P06401 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6022453 | 0.86 | AR (0.48) | PIK3CGPARGARPGRALDH1A1 | |
| SCHEMBL5865893 | 0.86 | PARG (0.50) | PIK3CGPARGARPGRNR3C1 | |
| SCHEMBL5865904 | 0.86 | PARG (0.47) | PIK3CGPARGARPGRNR3C1 | |
| SCHEMBL5865896 | 0.84 | AR (0.47) | PIK3CGPARGARPGRALDH1A1 | |
| SCHEMBL5865914 | 0.79 | HSD17B10 (0.57) | ARALDH1A1 | |
| SCHEMBL5865901 | 0.79 | HSD17B10 (0.57) | ARALDH1A1 | |
| SCHEMBL6077653 | 0.79 | AR (0.52) | ARPGRALDH1A1NR3C1NR3C2 | |
| SCHEMBL6022392 | 0.78 | POLB (0.49) | PARGPGRCA12CA9NR3C1 | |
| SCHEMBL6022431 | 0.78 | BRD1 (0.61) | PARG | |
| SCHEMBL5865870 | 0.77 | ALDH1A1 (0.45) | PARGARPGRALDH1A1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009052-B2 | Sulfonamide derivatives | WARNER LAMBERT COMPANY LLC (US) | 2006-03-07 | — | — | US | disclosed |
| EP-1608643-A1 | 6-SULFONAMIDE QUINOLINE AND CHROMENE DERIVATIVE AS ANDROGEN RECEPTOR ANTAGONISTS | Warner-Lambert Company LLC (US) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004083204-A1 | 6-SULFONAMIDE QUINOLINE AND CHROMENE DERIVATIVE AS ANDROGEN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY LLC (US) | 2004-09-30 | — | — | WO | disclosed |