Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM10 | O14672 | 20/20 | 1.00 |
| ▸ | MMP2 | P08253 | 16/20 | 1.00 |
| ▸ | ERBB2 | P04626 | 9/20 | 1.00 |
| ▸ | MMP9 | P14780 | 7/20 | 0.61 |
| ▸ | MMP1 | P03956 | 3/20 | 0.55 |
| ▸ | MMP3 | P08254 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL206346 | 1.00 | ADAM10 (1.00) | ADAM10MMP2ERBB2MMP9MMP1 | |
| SCHEMBL1363898 | 1.00 | ADAM10 (1.00) | ADAM10MMP2ERBB2MMP9MMP1 | |
| SCHEMBL1366383 | 1.00 | ADAM10 (1.00) | ADAM10MMP2ERBB2MMP9MMP1 | |
| SCHEMBL1364073 | 0.81 | ADAM10 (0.69) | ADAM10MMP2ERBB2MMP9MMP1 | |
| SCHEMBL1365985 | 0.81 | ADAM10 (0.69) | ADAM10MMP2ERBB2MMP9MMP1 | |
| SCHEMBL18429666 | 0.81 | ADAM10 (0.74) | ADAM10MMP2ERBB2MMP9MMP1 | |
| SCHEMBL1364953 | 0.81 | ADAM10 (0.74) | ADAM10MMP2ERBB2MMP9MMP1 | |
| SCHEMBL1363663 | 0.81 | ADAM10 (0.74) | ADAM10MMP2ERBB2MMP9MMP1 | |
| SCHEMBL1365501 | 0.78 | ADAM10 (0.70) | ADAM10MMP2ERBB2MMP9MMP1 | |
| SCHEMBL1365505 | 0.78 | ADAM10 (0.70) | ADAM10MMP2ERBB2MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613269-A2 | COMPOSITIONS, METHODS AND KITS RELATING TO HER-2 CLEAVAGE | Incyte Corporation (US) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004089294-A2 | COMPOSITIONS, METHODS AND KITS RELATING TO HER-2 CLEAVAGE | INCYTE CORPORATION (US) | 2004-10-21 | — | — | WO | disclosed |