Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 7/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6023712 | 0.84 | BMP1 (0.47) | BMP1MMP12 | |
| SCHEMBL6024296 | 0.81 | BMP1 (0.48) | BMP1 | |
| SCHEMBL6024219 | 0.80 | CNR2 (0.43) | CNR2 | |
| SCHEMBL6023658 | 0.80 | BMP1 (0.45) | BMP1MMP12 | |
| SCHEMBL6025846 | 0.78 | BMP1 (0.37) | BMP1 | |
| SCHEMBL6024707 | 0.78 | BMP1 (0.56) | BMP1CNR2MMP12 | |
| SCHEMBL6024471 | 0.78 | HDAC6 (0.46) | BMP1 | |
| SCHEMBL6023703 | 0.78 | BMP1 (0.56) | BMP1CNR2MMP12 | |
| SCHEMBL6024284 | 0.77 | ATM (0.43) | MMP12 | |
| SCHEMBL6024265 | 0.76 | BMP1 (0.41) | BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363873-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2006-01-04 | — | — | EP | disclosed |
| EP-1363873-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002070541-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITH KLINE BEECHAM CORPORATION (US) | 2002-09-12 | — | — | WO | disclosed |