Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 11/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 11/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6023450 | 0.94 | AKR1C3 (0.56) | AKR1C3AKR1C2AKR1C1PTGS1AKR1B10 | |
| SCHEMBL3828059 | 0.88 | AKR1C3 (0.65) | AKR1C3AKR1C2AKR1C1PTGS1AKR1B10 | |
| SCHEMBL10779075 | 0.86 | AKR1C3 (0.49) | AKR1C3AKR1C2AKR1C1PTGS1AKR1B10 | |
| SCHEMBL6024128 | 0.83 | AKR1C3 (0.52) | AKR1C3AKR1C2AKR1C1PTGS1AKR1B10 | |
| SCHEMBL11454673 | 0.81 | AKR1C3 (0.52) | AKR1C3AKR1C2KDM4EHTTACHE | |
| SCHEMBL8092960 | 0.81 | AKR1C3 (0.60) | AKR1C3AKR1C2AKR1C1PTGS1AKR1B10 | |
| SCHEMBL6023193 | 0.80 | AKR1C3 (0.47) | AKR1C3AKR1C2AKR1C1PTGS1AKR1B10 | |
| SCHEMBL6023191 | 0.80 | AKR1C3 (0.47) | AKR1C3AKR1C2AKR1C1PTGS1AKR1B10 | |
| SCHEMBL2495059 | 0.79 | AKR1C3 (0.58) | AKR1C3AKR1C2AKR1C1PTGS1AKR1B10 | |
| SCHEMBL298386 | 0.79 | TSHR (0.67) | AKR1C3AKR1C2AKR1C1PTGS1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060106037-A1 | Purin-6-one-derivatives | ALTANA PHARMA AG (DE) | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106037-A1 | Purin-6-one-derivatives | PDE4B, PDE4A, PDE2A | AKR1C3 1804/4885AKR1C2 2158/4885AKR1C1 2049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.