Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 11/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 11/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 3/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.42 |
| ▸ | GRM6 | O15303 | 2/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6023193 | 1.00 | AKR1C3 (0.47) | AKR1C3AKR1C2AKR1C1PTGS1GRM8 | |
| SCHEMBL11444860 | 0.82 | PDK1 (0.45) | AKR1C3AKR1C2GRM8GRM4GRM6 | |
| SCHEMBL11684128 | 0.81 | MEN1 (0.44) | AKR1C3AKR1C2AKR1C1PTGS1GRM8 | |
| SCHEMBL6023746 | 0.80 | AKR1C3 (0.56) | AKR1C3AKR1C2AKR1C1PTGS1KDM4E | |
| SCHEMBL6023450 | 0.80 | AKR1C3 (0.56) | AKR1C3AKR1C2AKR1C1PTGS1KDM4E | |
| SCHEMBL10779075 | 0.80 | AKR1C3 (0.49) | AKR1C3AKR1C2AKR1C1PTGS1AKR1B10 | |
| SCHEMBL11680895 | 0.80 | AKR1C3 (0.43) | AKR1C3AKR1C2AKR1C1PTGS1GRM8 | |
| SCHEMBL11680102 | 0.80 | AKR1C3 (0.45) | AKR1C3AKR1C2AKR1C1PTGS1GRM8 | |
| SCHEMBL11683356 | 0.79 | RAB9A (0.43) | AKR1C3AKR1C2AKR1C1PTGS1GRM8 | |
| SCHEMBL11683366 | 0.79 | RAB9A (0.43) | AKR1C3AKR1C2AKR1C1PTGS1GRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060106037-A1 | Purin-6-one-derivatives | ALTANA PHARMA AG (DE) | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106037-A1 | Purin-6-one-derivatives | PDE4B, PDE4A, PDE2A | AKR1C3 1804/4885AKR1C2 2158/4885AKR1C1 2049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.