SCHEMBL6023985

SCHEMBL6023985

CCCCCOc1cc(C=CC(=O)N2CCN(c3ccc(N=C(N)c4ccc[nH]4)cc3)CC2)cc(OCCCCC)c1O

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
THRB P10828 1/20 0.50
ACHE P22303 7/20 0.42
ME2 P23368 1/20 0.39
ME1 P48163 1/20 0.39
ME3 Q16798 1/20 0.39
TDP1 Q9NUW8 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6022708 0.99 MEN1 (0.51) MEN1KMT2ATHRBACHEME2
SCHEMBL6023702 0.99 MEN1 (0.51) MEN1KMT2ATHRBACHEME2
SCHEMBL6022488 0.98 MEN1 (0.47) MEN1KMT2ATHRBACHEME2
SCHEMBL6023460 0.85 MEN1 (0.50) MEN1KMT2ATHRBACHEME2
SCHEMBL6022684 0.84 MEN1 (0.51) MEN1KMT2ATHRBACHEME2
SCHEMBL6022614 0.84 MEN1 (0.51) MEN1KMT2ATHRBACHEME2
SCHEMBL7031605 0.84 MEN1 (0.51) MEN1KMT2ATHRBACHEME2
SCHEMBL6023965 0.84 MEN1 (0.49) MEN1KMT2ATHRBACHEME2
SCHEMBL6023977 0.84 MEN1 (0.49) MEN1KMT2ATHRBACHEME2
SCHEMBL6022701 0.83 MEN1 (0.51) MEN1KMT2ATHRBACHEME2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030162789-A1 4-Hydroxycinnamamide derivatives as antioxidants and pharmaceutical compositions containing them KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2003-08-28 US claimed
US-7078407-B2 4-hydroxycinnamamide derivatives as antioxidants and pharmaceutical compositions containing them KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2006-07-18 US disclosed
US-20030162789-A1 4-Hydroxycinnamamide derivatives as antioxidants and pharmaceutical compositions containing them KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2003-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162789-A1 4-Hydroxycinnamamide derivatives as antioxidants and pharmaceutical compositions containing them HTT, PARK7, NQO1 MEN1 3297/4885KMT2A 1377/4885THRB 4695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.