Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 9/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024017 | 0.89 | PDE2A (0.41) | PDE2A | |
| SCHEMBL6023204 | 0.89 | PDE2A (0.51) | PDE2A | |
| SCHEMBL6023837 | 0.89 | PDE2A (0.51) | PDE2A | |
| SCHEMBL6023263 | 0.87 | PDE2A (0.44) | PDE2A | |
| SCHEMBL6052089 | 0.81 | PDE2A (0.49) | PDE2A | |
| SCHEMBL7440929 | 0.80 | PDE2A (0.54) | PDE2A | |
| SCHEMBL6024717 | 0.77 | PDE2A (0.46) | PDE2A | |
| SCHEMBL6023491 | 0.77 | PDE2A (0.44) | PDE2A | |
| SCHEMBL6024368 | 0.77 | PDE2A (0.46) | PDE2A | |
| SCHEMBL6023972 | 0.76 | PDE2A (0.52) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060106037-A1 | Purin-6-one-derivatives | ALTANA PHARMA AG (DE) | 2006-05-18 | — | — | US | disclosed |
| EP-1601675-A1 | PURIN-6-ONE-DERIVATIVES | ALTANA Pharma AG (DE) | 2005-12-07 | — | — | EP | disclosed |
| WO-2004089953-A1 | PURIN-6-ONE-DERIVATIVES | ALTANA PHARMA AG (DE) | 2004-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106037-A1 | Purin-6-one-derivatives | PDE4B, PDE4A, PDE2A | PDE2A 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.