Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 5/20 | 0.49 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | PDE9A | O76083 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | CCNK | O75909 | 1/20 | 0.37 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6023263 | 0.89 | PDE2A (0.44) | PDE2ARNASEH1 | |
| SCHEMBL7440929 | 0.88 | PDE2A (0.54) | PDE2ARNASEH1 | |
| SCHEMBL6023837 | 0.83 | PDE2A (0.51) | PDE2ARNASEH1 | |
| SCHEMBL6023204 | 0.83 | PDE2A (0.51) | PDE2ARNASEH1 | |
| SCHEMBL6052091 | 0.82 | CDK1 (0.39) | CCNKCDK12 | |
| SCHEMBL6996492 | 0.82 | PDE2A (0.47) | PDE2ARNASEH1CCNKCDK12 | |
| SCHEMBL6998743 | 0.82 | PDE2A (0.42) | PDE2ARNASEH1PDE9APDE1C | |
| SCHEMBL6024137 | 0.81 | PDE2A (0.42) | PDE2A | |
| SCHEMBL6051959 | 0.79 | PDE2A (0.63) | PDE2ARNASEH1PDE9APDE1C | |
| SCHEMBL6051998 | 0.78 | PDE2A (0.42) | PDE2ARNASEH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060229242-A1 | Composition comprising a pulmonary surfactant and a pde2 inhibitor | ALTANA PHAZMA AG (DE) | 2006-10-12 | — | — | US | claimed |
| EP-1660132-A1 | COMPOSITION COMPRISING A PULMONARY SURFACTANT AND A PDE2 INHIBITOR | ALTANA Pharma AG (DE) | 2006-05-31 | — | — | EP | claimed |
| WO-2005021037-A1 | COMPOSITION COMPRISING A PULMONARY SURFACTANT AND A PDE2 INHIBITOR | ALTANA PHARMA AG (DE) | 2005-03-10 | — | — | WO | claimed |
| US-20060229242-A1 | Composition comprising a pulmonary surfactant and a pde2 inhibitor | ALTANA PHAZMA AG (DE) | 2006-10-12 | — | — | US | disclosed |
| EP-1660132-A1 | COMPOSITION COMPRISING A PULMONARY SURFACTANT AND A PDE2 INHIBITOR | ALTANA Pharma AG (DE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005021037-A1 | COMPOSITION COMPRISING A PULMONARY SURFACTANT AND A PDE2 INHIBITOR | ALTANA PHARMA AG (DE) | 2005-03-10 | — | — | WO | disclosed |