Sugi Predict

Sugi Predict / Compounds / SCHEMBL6024147

SCHEMBL6024147

SCHEMBL6024147

CCCCC[C@H](CN(O)C=O)C(=O)NNC(=O)N1C(=O)CC[C@H]1Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ BMP1 P13497 7/20 0.46
▸ MMP12 P39900 1/20 0.39
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ CNR2 P34972 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6023895 1.00 BMP1 (0.46) BMP1MMP12MEN1KMT2ACNR2
SCHEMBL6024632 0.80 BMP1 (0.46) BMP1MMP12
SCHEMBL6026461 0.80 BMP1 (0.46) BMP1MMP12
SCHEMBL6023703 0.78 BMP1 (0.56) BMP1MMP12MEN1KMT2ACNR2
SCHEMBL6024707 0.78 BMP1 (0.56) BMP1MMP12MEN1KMT2ACNR2
SCHEMBL1595891 0.75 BMP1 (0.57) BMP1MMP12
SCHEMBL1595896 0.75 BMP1 (0.57) BMP1MMP12
SCHEMBL1595893 0.75 BMP1 (0.57) BMP1MMP12
SCHEMBL1596337 0.74 BMP1 (0.49) BMP1MEN1KMT2A
SCHEMBL1596338 0.74 BMP1 (0.49) BMP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363873-A4 PEPTIDE DEFORMYLASE INHIBITORS SMITHKLINE BEECHAM CORP (US) 2006-01-04 — — EP disclosed
EP-1363873-A2 PEPTIDE DEFORMYLASE INHIBITORS SmithKline Beecham Corporation (US) 2003-11-26 — — EP disclosed
WO-2002070541-A2 PEPTIDE DEFORMYLASE INHIBITORS SMITH KLINE BEECHAM CORPORATION (US) 2002-09-12 — — WO disclosed