Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CASP6 | P55212 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | SENP2 | Q9HC62 | 5/20 | 0.34 |
| ▸ | SUMO2 | P61956 | 4/20 | 0.34 |
| ▸ | SUMO1 | P63165 | 4/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.34 |
| ▸ | SENP1 | Q9P0U3 | 4/20 | 0.34 |
| ▸ | SENP3 | Q9H4L4 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6023304 | 0.74 | GAA (0.35) | TP53GAACYP3A4TSHR | |
| SCHEMBL6023392 | 0.72 | MEN1 (0.33) | ALDH1A1HSD17B10CYP2C9CYP2C19SENP2 | |
| SCHEMBL6938187 | 0.69 | CYP3A4 (0.44) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL4429911 | 0.68 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TP53KDM4EMAPT | |
| SCHEMBL31697699 | 0.67 | BRD4 (0.49) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL428347 | 0.67 | CYP3A4 (0.42) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL1755154 | 0.67 | BRD4 (0.49) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL7032447 | 0.67 | CYP3A4 (0.48) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL1755030 | 0.67 | BRD4 (0.49) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL1412987 | 0.66 | TTR (0.46) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7144993-B2 | Process for the preparation of 4-methyl-7-aminoquinolones | CIBA SPECIALTY CHEMICALS CORP. (US) | 2006-12-05 | — | — | US | disclosed |
| US-20050222397-A1 | Process for the preparation of 4-methyl-7-aminoquinolones | CIBA SPECIALTY CHEMICALS CORP. | 2005-10-06 | — | — | US | disclosed |
| EP-1453809-A1 | PROCESS FOR THE PREPARATION OF 4-METHYL-7-AMINOQUINOLONES | Ciba SC Holding AG (CH) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050089-A1 | PROCESS FOR THE PREPARATION OF 4-METHYL-7-AMINOQUINOLONES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222397-A1 | Process for the preparation of 4-methyl-7-aminoquinolones | CBR1, CBR3, MRPL21 | ALDH1A1 2050/4885HSD17B10 587/4885CASP6 3697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.