Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 8/20 | 0.49 |
| ▸ | MMP12 | P39900 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSH | P09668 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5000934 | 0.81 | BMP1 (0.49) | BMP1MMP12 | |
| SCHEMBL4960111 | 0.78 | BMP1 (0.48) | BMP1MMP12 | |
| SCHEMBL6024544 | 0.76 | BMP1 (0.55) | BMP1MMP12 | |
| SCHEMBL6024091 | 0.75 | BMP1 (0.54) | BMP1MMP12 | |
| SCHEMBL1596524 | 0.75 | BMP1 (0.56) | BMP1MMP12CTSK | |
| SCHEMBL1596527 | 0.75 | BMP1 (0.56) | BMP1MMP12CTSK | |
| SCHEMBL1596529 | 0.75 | BMP1 (0.56) | BMP1MMP12CTSK | |
| SCHEMBL6024539 | 0.75 | BMP1 (0.51) | BMP1MMP12 | |
| SCHEMBL6023908 | 0.74 | BMP1 (0.63) | BMP1MMP12 | |
| SCHEMBL4959448 | 0.73 | BMP1 (0.44) | BMP1MMP12CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363873-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2006-01-04 | — | — | EP | disclosed |
| EP-1363873-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002070541-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITH KLINE BEECHAM CORPORATION (US) | 2002-09-12 | — | — | WO | disclosed |