SCHEMBL6024480

SCHEMBL6024480

CCOP(=O)(OCC)ON=C(C(=O)OC)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.48
NPSR1 Q6W5P4 1/20 0.41
LMNA P02545 2/20 0.40
POLB P06746 2/20 0.39
TSHR P16473 1/20 0.39
KMT2A Q03164 4/20 0.38
MEN1 O00255 3/20 0.38
NPC1 O15118 2/20 0.37
ALDH1A1 P00352 2/20 0.37
NR1I2 O75469 1/20 0.37
MAPT P10636 1/20 0.37
GAA P10253 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6025156 1.00 SMN1; SMN2 (0.48) SMN1; SMN2NPSR1LMNAPOLBTSHR
SCHEMBL6025082 0.89 SMN1; SMN2 (0.58) SMN1; SMN2NPSR1LMNATSHRKMT2A
SCHEMBL6025078 0.89 SMN1; SMN2 (0.58) SMN1; SMN2NPSR1LMNATSHRKMT2A
SCHEMBL6025101 0.88 SMN1; SMN2 (0.43) SMN1; SMN2NPSR1LMNAPOLBTSHR
SCHEMBL6025099 0.88 SMN1; SMN2 (0.43) SMN1; SMN2NPSR1LMNAPOLBTSHR
SCHEMBL6024494 0.85 SMN1; SMN2 (0.48) SMN1; SMN2LMNAPOLBTSHRKMT2A
SCHEMBL6025829 0.85 SMN1; SMN2 (0.48) SMN1; SMN2LMNAPOLBTSHRKMT2A
SCHEMBL6024866 0.84 TAS1R3 (0.43) SMN1; SMN2NPSR1LMNAPOLBTSHR
SCHEMBL6024867 0.84 TAS1R3 (0.43) SMN1; SMN2NPSR1LMNAPOLBTSHR
SCHEMBL28574555 0.80 SMN1; SMN2 (0.50) SMN1; SMN2LMNAPOLBTSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1163553-B1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SC HOLDING AG (CH) 2006-06-14 EP claimed
JP-2002538241-A 2002-11-12 JP claimed
EP-1163553-A1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS Ciba SC Holding AG (CH) 2001-12-19 EP claimed
WO-2000052530-A1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-09-08 WO claimed
EP-1163553-B1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SC HOLDING AG (CH) 2006-06-14 EP disclosed
EP-1635220-A2 Oxime derivatives and the use thereof as photoinitiators Ciba Specialty Chemicals Holding Inc. (CH) 2006-03-15 EP disclosed
US-6806024-B1 MIXTURES OF ADDITION POLYMERS AND ACTIVATORS COMPRISING NITROGEN COMPOUNDS, USED AS SUBSTRATE COATINGS FOR COLOR FILTERS CIBA SPECIALTY CHEMICALS CORPORATION 2004-10-19 US disclosed
EP-1163553-A1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS Ciba SC Holding AG (CH) 2001-12-19 EP disclosed
WO-2000052530-A1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-09-08 WO disclosed