SCHEMBL6024739

SCHEMBL6024739

CCCCC[C@H](CN(O)C=O)C(=O)N(N)C(=O)c1ccccc1-c1nc(OC)cc(OC)n1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BMP1 P13497 7/20 0.41
MMP12 P39900 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6023693 0.83 BMP1 (0.48) BMP1MMP12
SCHEMBL6024706 0.81 BMP1 (0.40) BMP1MMP12
SCHEMBL6023843 0.75 BMP1 (0.44) BMP1MMP12
SCHEMBL6024774 0.75 BMP1 (0.41) BMP1MMP12
SCHEMBL6024283 0.74 BMP1 (0.42) BMP1
SCHEMBL6024770 0.74 BMP1 (0.44) BMP1MMP12
SCHEMBL6024206 0.73 HCRTR1 (0.40) BMP1
SCHEMBL6024907 0.73 HDAC3 (0.39) BMP1MMP12
SCHEMBL6024415 0.72 BMP1 (0.39) BMP1MMP12
SCHEMBL6023716 0.71 BMP1 (0.40) BMP1MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363873-A4 PEPTIDE DEFORMYLASE INHIBITORS SMITHKLINE BEECHAM CORP (US) 2006-01-04 EP disclosed
EP-1363873-A2 PEPTIDE DEFORMYLASE INHIBITORS SmithKline Beecham Corporation (US) 2003-11-26 EP disclosed
WO-2002070541-A2 PEPTIDE DEFORMYLASE INHIBITORS SMITH KLINE BEECHAM CORPORATION (US) 2002-09-12 WO disclosed