Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.53 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.53 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.53 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.53 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.53 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.53 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.75 |
| ▸ | MEN1 | O00255 | 4/20 | 0.75 |
| ▸ | MAPT | P10636 | 3/20 | 0.75 |
| ▸ | TP53 | P04637 | 1/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.75 |
| ▸ | HTT | P42858 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6224118 | 1.00 | KMT2A (0.75) | KMT2AMEN1MAPTTP53CYP1A2 | |
| Bromide SCHEMBL7141677 | 1.00 | KMT2A (0.75) | KMT2AMEN1MAPTTP53CYP1A2 | |
| Bromide SCHEMBL2868130 | 1.00 | KMT2A (0.75) | KMT2AMEN1MAPTTP53CYP1A2 | |
| Bromide SCHEMBL4769564 | 0.98 | KMT2A (0.72) | KMT2AMEN1MAPTTP53CYP1A2 | |
| Bromide SCHEMBL28044241 | 0.98 | KMT2A (0.72) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL1108035 | 0.98 | KMT2A (0.78) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL7968623 | 0.98 | KMT2A (0.78) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL12138754 | 0.98 | KMT2A (0.78) | KMT2AMEN1MAPTTP53CYP1A2 | |
| Bromide SCHEMBL19664670 | 0.96 | KMT2A (0.75) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL5221222 | 0.96 | KMT2A (0.74) | KMT2AMEN1MAPTTP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368623-B1 | TUNGSTEN-PROCESSING SLURRY WITH CATIONIC SURFACTANT AND CYCLODEXTRIN | CMC MAT INC (US) | 2022-11-30 | — | — | EP | claimed |
| EP-1488277-A4 | SWITCHABLE ELECTRO-OPTICAL LAMINATES | AVERY DENNISON CORP (US) | 2006-08-16 | — | — | EP | claimed |
| US-20050277297-A1 | Copper nanocrystals and methods of producing same | WINTER CHARLES H | 2005-12-15 | — | — | US | claimed |
| US-6963435-B2 | Switchable electro-optical laminates | AVERY DENNISON CORPORATION (US) | 2005-11-08 | — | — | US | claimed |
| US-6887297-B2 | Copper nanocrystals and methods of producing same | WAYNE STATE UNIVERSITY (US) | 2005-05-03 | — | — | US | claimed |
| US-20050083564-A1 | Switchable electro-optical laminates | MALLYA PRAKASH (US) | 2005-04-21 | — | — | US | claimed |
| EP-1488277-A2 | SWITCHABLE ELECTRO-OPTICAL LAMINATES | AVERY DENNISON CORPORATION (US) | 2004-12-22 | — | — | EP | claimed |
| WO-2004043634-A9 | COPPER NANOCRYSTALS AND METHODS OF PRODUCING THE SAME | UNIV WAYNE STATE (US) | 2004-09-16 | — | — | WO | claimed |
| WO-2004043634-A1 | COPPER NANOCRYSTALS AND METHODS OF PRODUCING THE SAME | WAYNE STATE UNIVERSITY (US) | 2004-05-27 | — | — | WO | claimed |
| US-20040089101-A1 | Copper nanocrystals and methods of producing same | WAYNE STATE UNIVERSITY | 2004-05-13 | — | — | US | claimed |
| WO-2003083523-A2 | SWITCHABLE ELECTRO-OPTICAL LAMINATES | AVERY DENNISON CORPORATION (US) | 2003-10-09 | — | — | WO | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| EP-0615855-B1 | Recording sheets containing pyridinium and/or piperazinum compounds | XEROX CORP (US) | 1997-05-14 | — | — | EP | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| US-5441795-A | Piperazinium compounds | XEROX CORPORATION (US) | 1995-08-15 | — | — | US | claimed |
| EP-0615855-A1 | Recording sheets containing pyridinium and/or piperazinum compounds | XEROX CORPORATION (US) | 1994-09-21 | — | — | EP | claimed |