SCHEMBL1108035

SCHEMBL1108035

CCCCCC[n+]1ccc(-c2ccncc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.78
MEN1 O00255 2/20 0.78
MAPT P10636 2/20 0.78
CYP2D6 P10635 2/20 0.78
TP53 P04637 1/20 0.78
CYP1A2 P05177 1/20 0.78
CYP2C9 P11712 1/20 0.78
CYP2C19 P33261 1/20 0.78
HTT P42858 4/20 0.75
SMN1; SMN2 Q16637 3/20 0.75
LMNA P02545 2/20 0.75
KDM4E B2RXH2 1/20 0.75
NPC1 O15118 1/20 0.75
RAB9A P51151 1/20 0.75
MAPK1 P28482 1/20 0.55
CASP2 P42575 1/20 0.55
RAD52 P43351 3/20 0.53
HSPD1 P10809 1/20 0.53
HSPE1 P61604 1/20 0.53
CHRM2 P08172 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12138754 1.00 KMT2A (0.78) KMT2AMEN1MAPTCYP2D6TP53
SCHEMBL7968623 1.00 KMT2A (0.78) KMT2AMEN1MAPTCYP2D6TP53
Bromide SCHEMBL2868130 0.98 KMT2A (0.75) KMT2AMEN1MAPTCYP2D6TP53
Bromide SCHEMBL19664670 0.98 KMT2A (0.75) KMT2AMEN1MAPTCYP2D6TP53
Bromide SCHEMBL7141677 0.98 KMT2A (0.75) KMT2AMEN1MAPTCYP2D6TP53
Bromide SCHEMBL6024741 0.98 KMT2A (0.75) KMT2AMEN1MAPTCYP2D6TP53
Bromide SCHEMBL6224118 0.98 KMT2A (0.75) KMT2AMEN1MAPTCYP2D6TP53
SCHEMBL5221222 0.98 KMT2A (0.74) KMT2AMEN1MAPTCYP2D6TP53
Iodide SCHEMBL16563204 0.96 HTT (0.76) KMT2AMEN1MAPTCYP2D6TP53
Bromide SCHEMBL4769564 0.96 KMT2A (0.72) KMT2AMEN1MAPTCYP2D6TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240069257-A1 CHOLESTERIC LIQUID CRYSTAL LAYER, METHOD OF FORMING CHOLESTERIC LIQUID CRYSTAL LAYER, LAMINATE, LIGHT GUIDE ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2024-02-29 US disclosed
WO-2024039181-A1 MOF/VIOLOGEN HYBRID IONOGEL-BASED ELECTROCHROMIC MATERIAL, METHOD FOR PREPARING SAME, AND ALL-IN-ONE ELECTROCHROMIC DEVICE COMPRISING SAME 명지대학교 산학협력단 2024-02-22 WO disclosed
US-11828960-B2 Cholesteric liquid crystal layer, method of forming cholesteric liquid crystal layer, laminate, light guide element, and image display device FUJIFILM CORPORATION (JP) 2023-11-28 US disclosed
US-8153246-B2 Optical compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-20120013966-A1 ELECTROCHROMIC MATERIAL AND ELECTROCHROMIC DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-01-19 US disclosed
US-7658864-B2 Liquid crystal composition, optical compensation film and liquid crystal display device FUJIFILM CORPORATION (JP) 2010-02-09 US disclosed
US-20090273740-A1 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-11-05 US disclosed
US-20090009693-A1 Liquid Crystal Composition, Optical Compensation Film and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2009-01-08 US disclosed
US-7311950-B2 Composition, optical compensatory film and liquid crystal display FUJIFILM CORPORATION (JP) 2007-12-25 US disclosed
WO-2007037497-A1 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-04-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120013966-A1 ELECTROCHROMIC MATERIAL AND ELECTROCHROMIC DEVICE INCLUDING THE SAME EPX, EPN1, HCN2 KMT2A 675/4885MEN1 652/4885MAPT 3483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.