Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.49 |
| ▸ | RELA | Q04206 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | ACR | P10323 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13882235 | 0.99 | LMNA (0.48) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL13882247 | 0.95 | LMNA (0.54) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL13882233 | 0.95 | LMNA (0.54) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL13623372 | 0.94 | KMT2A (0.45) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL12288706 | 0.94 | LMNA (0.44) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL12926259 | 0.93 | LMNA (0.44) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL7152964 | 0.93 | LMNA (0.44) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL14099006 | 0.92 | NPC1 (0.43) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL14099005 | 0.92 | NPC1 (0.43) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL12769757 | 0.92 | NPC1 (0.43) | LMNANPC1NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337602-B1 | POLYMERIZABLE LIQUID CRYSTALLINE DIOXETANES, THEIR PREPARATION AND USE | KONINKL PHILIPS ELECTRONICS NV (NL) | 2006-04-12 | — | — | EP | disclosed |
| US-6660344-B2 | A crosslinked polyether copolymer for liquid crystalline device; shrinkage inhibition | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2003-12-09 | — | — | US | disclosed |
| US-20030111640-A1 | Polymerizable liquid crystalline dioxetanes, their preparation and use | KONINKLIJKE PHILIPS ELECTRONICS N.V. | 2003-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030111640-A1 | Polymerizable liquid crystalline dioxetanes, their preparation and use | SCO2, PYM1, CNOT1 | LMNA 3633/4885NPC1 4124/4885NFKB1 4493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.