Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | TPMT | P51580 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13875418 | 1.00 | TSHR (0.54) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2124837 | 0.84 | MAPK1 (0.58) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6025361 | 0.82 | MAPT (0.51) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13875414 | 0.81 | TSHR (0.44) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13890438 | 0.80 | TSHR (0.66) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13875413 | 0.79 | CA12 (0.48) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3758910 | 0.79 | TSHR (0.76) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29618985 | 0.79 | TSHR (0.76) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11245864 | 0.78 | MAPT (0.73) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14845454 | 0.78 | TSHR (0.63) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163553-B1 | OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2006-06-14 | — | — | EP | disclosed |
| EP-1635220-A2 | Oxime derivatives and the use thereof as photoinitiators | Ciba Specialty Chemicals Holding Inc. (CH) | 2006-03-15 | — | — | EP | disclosed |
| US-6806024-B1 | MIXTURES OF ADDITION POLYMERS AND ACTIVATORS COMPRISING NITROGEN COMPOUNDS, USED AS SUBSTRATE COATINGS FOR COLOR FILTERS | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-10-19 | — | — | US | disclosed |
| EP-1163553-A1 | OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000052530-A1 | OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-09-08 | — | — | WO | disclosed |