Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13875415 | 0.84 | MAPT (0.41) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13875419 | 0.84 | MAPT (0.39) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6025283 | 0.81 | TSHR (0.54) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13875418 | 0.81 | TSHR (0.54) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13875382 | 0.77 | ALDH1A1 (0.39) | MAPTMAPK1KMT2ACES2CES1 | |
| SCHEMBL13875422 | 0.77 | RAB9A (0.42) | TSHRMAPTSMN1; SMN2MAPK1KMT2A | |
| SCHEMBL13875442 | 0.77 | PLK1 (0.36) | TSHRMAPTPOLBSMN1; SMN2KMT2A | |
| SCHEMBL2124837 | 0.75 | MAPK1 (0.58) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13875413 | 0.73 | CA12 (0.48) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13875434 | 0.72 | CES2 (0.46) | CYP1A2CYP3A4CYP2C19MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090092768-A1 | Process for the Production of Strongly Adherent Coatings | CIBA SPECIALTY CHEMICALS CORP. | 2009-04-09 | — | — | US | disclosed |