Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 17/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2956204 | 1.00 | AR (0.57) | ARPGRNR3C2 | |
| SCHEMBL13216320 | 0.91 | AR (0.67) | ARPGR | |
| SCHEMBL2955405 | 0.91 | AR (0.67) | ARPGR | |
| SCHEMBL2963011 | 0.91 | AR (0.67) | ARPGR | |
| SCHEMBL6026490 | 0.91 | AR (0.67) | ARPGR | |
| SCHEMBL13215950 | 0.91 | AR (0.67) | ARPGR | |
| SCHEMBL6025855 | 0.91 | AR (0.67) | ARPGR | |
| SCHEMBL13586658 | 0.86 | AR (0.51) | AR | |
| SCHEMBL14138413 | 0.84 | AR (0.49) | AR | |
| SCHEMBL14138454 | 0.84 | AR (0.49) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506178-A4 | BICYCLIC MODULATORS OF ANDROGEN RECEPTOR FUNCTION | BRISTOL MYERS SQUIBB CO (US) | 2006-05-24 | — | — | EP | disclosed |
| EP-1506178-A2 | BICYCLIC MODULATORS OF ANDROGEN RECEPTOR FUNCTION | Bristol-Myers Squibb Company (US) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003096980-A2 | BICYCLIC MODULATORS OF ANDROGEN RECEPTOR FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-11-27 | — | — | WO | disclosed |