Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71045 | 0.83 | TSHR (0.44) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10344292 | 0.81 | TSHR (0.52) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3292550 | 0.81 | TSHR (0.43) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5503634 | 0.77 | TSHR (0.48) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7302690 | 0.77 | TSHR (0.48) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7302683 | 0.77 | TSHR (0.48) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8079929 | 0.76 | TSHR (0.52) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL547986 | 0.76 | SLC6A2 (0.47) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL14667806 | 0.76 | TSHR (0.46) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6774650 | 0.75 | TSHR (0.57) | TSHRIDO1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107383139-A | The method that a kind of β cholanic acid new derivatives of 7 oxo of 3 α hydroxyls 5 prepare shellfish cholic acid difficult to understand | 杭州和泽医药科技有限公司 | 2017-11-24 | — | — | CN | disclosed |
| CN-103450113-B | Thiadiazine-triketones-substituted derivative, preparation method thereof and application | UNIV SHANDONG | 2014-12-10 | — | — | CN | disclosed |
| CN-103450113-A | Thiadiazine-triketones-substituted derivative, preparation method thereof and application | UNIV SHANDONG | 2013-12-18 | — | — | CN | disclosed |
| EP-1369490-B1 | Method of preparing a composition containing hygromycin A and epi-hygromycin | PFIZER PROD INC (US) | 2006-02-08 | — | — | EP | disclosed |
| EP-1369490-A1 | Method of preparing a composition containing hygromycin A and epi-hygromycin | Pfizer Products Inc. (US) | 2003-12-10 | — | — | EP | disclosed |
| EP-1075483-B1 | HYGROMYCIN A DERIVATIVES | PFIZER PROD INC (US) | 2003-12-03 | — | — | EP | disclosed |
| US-6313100-B1 | ANTIBACTERIAL, ANTIPROTOZOA AGENTS | PFIZER INC | 2001-11-06 | — | — | US | disclosed |
| EP-1075483-A2 | HYGROMYCIN A DERIVATIVES | Pfizer Products Inc. (US) | 2001-02-14 | — | — | EP | disclosed |
| WO-1999057125-A2 | HYGROMYCIN A DERIVATIVES | PFIZER PRODUCTS INC. (US) | 1999-11-11 | — | — | WO | disclosed |
| US-5760018-A | Gem-disubstituted azacyclic tachykinin antagonists | MERCK SHARP & DOHME LTD. (GB) | 1998-06-02 | — | — | US | disclosed |
| EP-0739336-A1 | GEM-DISUBSTITUTED AZACYCLIC TACHYKININ ANTAGONISTS | MERCK SHARP & DOHME LTD. (GB) | 1996-10-30 | — | — | EP | disclosed |
| WO-1995028413-A1 | 17β-SUBSTITUTED 3-CARBOXY STEROIDS THAT INHIBIT 5-α-REDUCTASE | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-26 | — | — | WO | disclosed |
| WO-1995019344-A1 | GEM-DISUBSTITUTED AZACYCLIC TACHYKININ ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1995-07-20 | — | — | WO | disclosed |