Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BMP1 | P13497 | 6/20 | 0.35 |
| ▸ | Q9HBH1 | 1/20 | 0.33 | |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024066 | 0.87 | HPGD (0.35) | BMP1 | |
| SCHEMBL6024383 | 0.80 | BMP1 (0.42) | BMP1PDFMMP12 | |
| SCHEMBL6026290 | 0.77 | MEN1 (0.38) | SMN1; SMN2 | |
| SCHEMBL6024579 | 0.75 | BMP1 (0.39) | BMP1MMP12 | |
| SCHEMBL6024441 | 0.74 | BMP1 (0.40) | BMP1MMP12 | |
| SCHEMBL4959841 | 0.73 | BMP1 (0.42) | BMP1PDFMMP12 | |
| SCHEMBL4960426 | 0.73 | BMP1 (0.42) | BMP1PDFMMP12 | |
| SCHEMBL6024047 | 0.73 | BMP1 (0.34) | BMP1 | |
| SCHEMBL4957394 | 0.71 | BMP1 (0.42) | BMP1PDFMMP12 | |
| SCHEMBL1596009 | 0.70 | BMP1 (0.44) | BMP1PDFMMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019003-B2 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2006-03-28 | — | — | US | disclosed |