Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPP5A | Q14642 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 3/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3431004 | 0.83 | INPP5A (0.42) | INPP5AS1PR4S1PR1S1PR3ANPEP | |
| SCHEMBL3429410 | 0.75 | — | — | |
| SCHEMBL2238021 | 0.71 | — | — | |
| SCHEMBL1484842 | 0.71 | — | — | |
| SCHEMBL3431002 | 0.70 | INPP5A (0.42) | INPP5AS1PR4S1PR1S1PR3ANPEP | |
| SCHEMBL18501083 | 0.69 | ANPEP (0.40) | S1PR4S1PR1S1PR3S1PR5ANPEP | |
| SCHEMBL7113872 | 0.69 | KDM4E (0.50) | ANPEPERAP2CXCR4DPP7 | |
| SCHEMBL11461187 | 0.69 | KDM4E (0.50) | ANPEPERAP2CXCR4DPP7 | |
| SCHEMBL1153406 | 0.69 | KDM4E (0.50) | ANPEPERAP2CXCR4DPP7 | |
| SCHEMBL131659 | 0.69 | KDM4E (0.50) | ANPEPERAP2CXCR4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613619-A1 | QUINAZOLINE DERIVATIVES FOR TREATMENT OF CANCER | AstraZeneca AB (SE) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004094410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-11-04 | — | — | WO | disclosed |