Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | CXCR3 | P49682 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026829 | 0.76 | TRPV1 (0.44) | TRPV1CXCR3KMT2AMEN1HTT | |
| Alcohol SCHEMBL26655335 | 0.73 | TRPV1 (0.91) | TRPV1CXCR3KMT2APDE10AKCNH2 | |
| SCHEMBL15957766 | 0.72 | TRPV1 (0.58) | TRPV1CXCR3HTTPDE10AALDH1A1 | |
| SCHEMBL29383546 | 0.72 | TRPV1 (1.00) | TRPV1CXCR3KMT2APDE10AKCNH2 | |
| SCHEMBL1066896 | 0.72 | TRPV1 (1.00) | TRPV1CXCR3KMT2APDE10AKCNH2 | |
| SCHEMBL1663702 | 0.71 | TRPV1 (0.77) | TRPV1CXCR3KMT2APDE10AALDH1A1 | |
| SCHEMBL12374601 | 0.69 | TRPV1 (0.51) | TRPV1ALDH1A1KDM4EGAAGLA | |
| SCHEMBL1664439 | 0.69 | TRPV1 (0.74) | TRPV1CXCR3HTTPDE10AALDH1A1 | |
| SCHEMBL10446275 | 0.68 | TRPV1 (0.56) | TRPV1CXCR3KMT2AMEN1ALDH1A1 | |
| SCHEMBL1663818 | 0.67 | TRPV1 (0.64) | TRPV1CXCR3KMT2AMEN1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264420-A1 | Compounds, compositions, and methods | CYTOKINETICS, INC. (US) | 2006-11-23 | — | — | US | disclosed |
| EP-1539180-A4 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2006-08-30 | — | — | EP | disclosed |
| EP-1539180-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040048853-A1 | Compounds, compositions, and methods | CYTOKINETICS, INC. | 2004-03-11 | — | — | US | disclosed |
| WO-2004018058-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264420-A1 | Compounds, compositions, and methods | ALPP, PCNA, MKI67 | TRPV1 4539/4885CXCR3 3073/4885KMT2A 1458/4885 |
| US-20040048853-A1 | Compounds, compositions, and methods | ALPP, PCNA, MKI67 | TRPV1 4539/4885CXCR3 3073/4885KMT2A 1458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.