Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.55 |
| ▸ | CA2 | P00918 | 5/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8590990 | 0.85 | CA1 (0.55) | CA1CA2CA7CA9CA12 | |
| SCHEMBL7190291 | 0.82 | CA1 (0.58) | CA1CA2CA7CA9CA12 | |
| SCHEMBL4126810 | 0.80 | CA1 (0.55) | CA1CA2CA7CA9CA12 | |
| SCHEMBL10112753 | 0.79 | CA1 (0.61) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1538395 | 0.79 | CA1 (0.61) | CA1CA2CA7CA9CA12 | |
| SCHEMBL678596 | 0.79 | CA1 (0.61) | CA1CA2CA7CA9CA12 | |
| SCHEMBL83852 | 0.79 | CA1 (0.61) | CA1CA2CA7CA9CA12 | |
| SCHEMBL78643 | 0.79 | MAPT (0.64) | CA1CA2CA7CA9CA12 | |
| SCHEMBL3098811 | 0.79 | CA1 (0.61) | CA1CA2CA7CA9CA12 | |
| SCHEMBL3665016 | 0.79 | MAPT (0.64) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7002010-B2 | Process for the preparation of morpholinones as light stabilizers | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-02-21 | — | — | US | disclosed |
| US-20040024252-A1 | Process for the preparation of morpholinones as light stabilizers | CIBA SPECIALTY CHEMICALS CORP. | 2004-02-05 | — | — | US | disclosed |
| EP-1341775-A2 | PROCESS FOR THE PREPARATION OF MORPHOLINONES | Ciba SC Holding AG (CH) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002048123-A2 | PROCESS FOR THE PREPARATION OF MORPHOLINONES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-06-20 | — | — | WO | disclosed |
| US-4742073-A | ANTIGLAUCOMA | BUNDGAARD HANS (DK) | 1988-05-03 | — | — | US | disclosed |
| EP-0106541-A2 | Pilocarpine prodrugs | Bundgaard, Hans (DK) | 1984-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040024252-A1 | Process for the preparation of morpholinones as light stabilizers | TMT1A, SEM1, MITF | CA1 3597/4885CA2 3841/4885CA7 2552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.