Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 8/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21239604 | 0.79 | TACR1 (0.61) | TACR1TSHRCA1CA2CA7 | |
| SCHEMBL8703481 | 0.78 | TACR1 (0.51) | TACR1TSHRCA1CA2CA7 | |
| SCHEMBL10435907 | 0.78 | TSHR (0.42) | TACR1TSHRSMN1; SMN2 | |
| SCHEMBL16321476 | 0.78 | TACR1 (0.70) | TACR1TSHRCA1CA2CA7 | |
| SCHEMBL4988525 | 0.78 | TACR1 (0.70) | TACR1TSHRCA1CA2CA7 | |
| SCHEMBL18580091 | 0.78 | TACR1 (0.70) | TACR1TSHRCA1CA2CA7 | |
| SCHEMBL11370887 | 0.78 | TSHR (0.56) | TACR1TSHRCA1CA2CA7 | |
| SCHEMBL21848157 | 0.76 | TSHR (0.67) | TACR1TSHRCA1CA2CA7 | |
| SCHEMBL1520889 | 0.76 | CA1 (0.59) | TACR1TSHRCA1CA2CA7 | |
| SCHEMBL12519870 | 0.76 | TACR1 (0.58) | TACR1TSHRCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664153-A1 | MOLECULAR WEIGHT INCREASE AND MODIFICATION OF POLYCONDENSATES | Ciba SC Holding AG (CH) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005030834-A1 | MOLECULAR WEIGHT INCREASE AND MODIFICATION OF POLYCONDENSATES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-04-07 | — | — | WO | disclosed |
| US-20010009939-A1 | STABILIZERS FOR POWDER COATINGS | CIBA SPECIALTY CHEMICALS CORP. | 2001-07-26 | — | — | US | disclosed |
| US-3992441-A | ANTILIPEMIC | PFIZER INC. (US) | 1976-11-16 | — | — | US | disclosed |