SCHEMBL10435907

SCHEMBL10435907

CCOCC([O])c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
POLB P06746 1/20 0.42
OPRM1 P35372 1/20 0.41
OPRD1 P41143 1/20 0.41
OPRK1 P41145 1/20 0.41
OPRL1 P41146 1/20 0.41
LMNA P02545 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
ALDH1A1 P00352 2/20 0.39
MMP8 P22894 1/20 0.39
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
PKM P14618 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.35
HKDC1 Q2TB90 1/20 0.35
TACR1 P25103 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2279792 0.78 HKDC1 (0.46) TSHRPOLBOPRM1OPRD1OPRK1
SCHEMBL1785539 0.78 SMN1; SMN2 (0.47) TSHRPOLBOPRM1OPRD1OPRK1
SCHEMBL27417242 0.78 HPGD (0.43) TSHROPRM1OPRD1OPRK1OPRL1
SCHEMBL6203525 0.78 AOC3 (0.41) LMNA
SCHEMBL6026682 0.78 TACR1 (0.58) TSHRSMN1; SMN2TACR1
SCHEMBL6202675 0.77 TP53 (0.46) TSHRLMNASMN1; SMN2ALDH1A1CYP1A2
SCHEMBL6205524 0.77 L3MBTL1 (0.50) ALDH1A1L3MBTL1
SCHEMBL1911096 0.77 TAAR1 (0.50) TSHRPOLBOPRM1OPRD1OPRK1
SCHEMBL1911339 0.77 SCN4A (0.59) TACR1
SCHEMBL12846898 0.77 TAAR1 (0.50) TSHRPOLBOPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102967970-B The manufacture method of array base palte, liquid crystal display cells and array base palte JSR CO., LTD. (JP) 2016-05-25 CN disclosed
CN-101646718-B Curable resin composition, protective film, and method for forming protective film JSR CORP JP 2013-04-03 CN disclosed
CN-102967970-A Array substrate, liquid display element, and method for manufacturing array subsrtate JSR CORP 2013-03-13 CN disclosed
CN-101153121-B Radiation-sensitive resin composition for spacer, spacer and method for forming the same JSR CORP 2012-11-14 CN disclosed
CN-101025567-B Radiation-sensitive resin composition, method for forming spacer and spacer JSR CO., LTD. (JP) 2011-12-14 CN disclosed
CN-101646718-A The formation method of curable resin composition, protective membrane and protective membrane JSR CORP JP 2010-02-10 CN disclosed
CN-100506877-C Curable resin composition, protective film, and method for forming same JSR CORP (JP) 2009-07-01 CN disclosed
CN-101153121-A Radiation-sensitive resin composition for spacer, spacer and method for forming the same JSR CORP (JP) 2008-04-02 CN disclosed
CN-101025567-A Radiation-sensitive resin composition, method for forming spacer and spacer JSR CORP (JP) 2007-08-29 CN disclosed
CN-1898291-A Curable resin composition, overcoats, and process for formation thereof JSR CORP (JP) 2007-01-17 CN disclosed
CN-1332205-A Radiation-sensitive resin composition JSR CORP (JP) 2002-01-23 CN disclosed
EP-0393607-A2 Phenylcarboxylic acid derivatives having a hetero ring OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-10-24 EP disclosed