SCHEMBL6026850

SCHEMBL6026850

CCCCOC(=O)c1c(O)cc(C)oc1=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.60
ESR1 P03372 10/20 0.54
KMT2A Q03164 1/20 0.50
CNR1 P21554 2/20 0.49
CNR2 P34972 2/20 0.49
AKR1C4 P17516 1/20 0.48
AKR1C3 P42330 1/20 0.48
AKR1C2 P52895 1/20 0.48
AKR1C1 Q04828 1/20 0.48
NPC1 O15118 1/20 0.47
PKM P14618 1/20 0.47
RAB9A P51151 1/20 0.47
LMNA P02545 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
CYP2C19 P33261 1/20 0.44
NR1H2 P55055 1/20 0.44
RNASEL Q05823 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6026715 0.96 ELANE (0.63) ELANEESR1KMT2ACNR1CNR2
SCHEMBL6027463 0.91 ELANE (0.56) ELANEESR1KMT2ANPC1PKM
SCHEMBL6026762 0.86 NR1H2 (0.59) ELANEKMT2ANPC1PKMRAB9A
SCHEMBL6026870 0.82 ELANE (0.46) ELANEKMT2ANPC1PKMRAB9A
SCHEMBL6026766 0.81 KMT2A (0.45) ELANEKMT2ANPC1PKMRAB9A
SCHEMBL6026747 0.78 ELANE (0.48) ELANEKMT2ANPC1PKMRAB9A
SCHEMBL6026095 0.78 ELANE (0.48) ELANEKMT2ANPC1PKMRAB9A
SCHEMBL7965056 0.77 CYP3A4 (0.51) ELANEKMT2ANPC1PKMRAB9A
SCHEMBL6026922 0.77 ELANE (0.52) ELANEKMT2ANPC1PKMRAB9A
SCHEMBL10337601 0.77 ELANE (0.97) ELANEKMT2ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7067523-B2 Use of pyrone carboxylates for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-06-27 US disclosed
US-20050159479-A1 Use of pyrone carboxylates for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-21 US disclosed
WO-2003099008-A1 USE OF PYRONE CARBOXYLATES FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050159479-A1 Use of pyrone carboxylates for controlling pests TET1, TET3, CNPY3 ELANE 2080/4885ESR1 3490/4885KMT2A 2113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.