Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 9/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | ELANE | P08246 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026762 | 0.83 | NR1H2 (0.59) | CYP3A4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6027019 | 0.81 | MEN1 (0.48) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL6027416 | 0.81 | MEN1 (0.51) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL6026809 | 0.79 | MEN1 (0.55) | CYP3A4ACHEMEN1KMT2AMAPT | |
| SCHEMBL1308058 | 0.79 | KMT2A (0.59) | CYP3A4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6026860 | 0.79 | MEN1 (0.46) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL6027463 | 0.79 | ELANE (0.56) | CYP3A4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6026922 | 0.79 | ELANE (0.52) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL23146904 | 0.78 | ELANE (0.58) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11227804 | 0.78 | KMT2A (0.58) | CYP3A4MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |