Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.43 |
| ▸ | FABP3 | P05413 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18493974 | 0.92 | CYP3A4 (0.42) | FABP4FABP3PPARGPRNPRXFP1 | |
| SCHEMBL18493977 | 0.86 | HPGD (0.39) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL7541648 | 0.86 | ALDH1A1 (0.40) | FABP4FABP3PPARGPRNPRXFP1 | |
| SCHEMBL29089099 | 0.86 | ALDH1A1 (0.43) | PPARGNR2E3NCOR2ALDH1A1HPGD | |
| SCHEMBL29380553 | 0.86 | ALDH1A1 (0.43) | PPARGNR2E3NCOR2ALDH1A1HPGD | |
| SCHEMBL4419668 | 0.86 | MAPT (0.49) | ALDH1A1HPGDLMNAMAPTKDM4E | |
| SCHEMBL28660408 | 0.85 | TTR (0.46) | PDE10AALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL29059655 | 0.84 | ALDH1A1 (0.39) | FABP4FABP3PPARGPRNPRXFP1 | |
| SCHEMBL9815280 | 0.84 | CYP3A4 (0.48) | FABP4FABP3ALDH1A1HPGDMAPT | |
| SCHEMBL27476638 | 0.83 | ALDH1A1 (0.38) | FABP4FABP3PPARGNR2E3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697339-A1 | 3-(4-BENZYLOXYPHENYL)PROPANOIC ACID DERIVATIVES | Takeda Pharmaceutical Company Limited (JP) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005063729-A1 | 3-(4-BENZYLOXYPHENYL)PROPANOIC ACID DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-07-14 | — | — | WO | disclosed |