Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11769303 | 0.86 | ELANE (0.78) | ELANEGAAKMT2AMEN1L3MBTL1 | |
| SCHEMBL27921576 | 0.83 | ELANE (0.89) | ELANEKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL27035914 | 0.83 | ELANE (0.88) | ELANEKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL27035967 | 0.83 | ELANE (0.88) | ELANEKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL27035935 | 0.83 | ELANE (0.88) | ELANEKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL27035891 | 0.83 | ELANE (0.88) | ELANEKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL27035911 | 0.83 | ELANE (0.88) | ELANEKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL10337601 | 0.82 | ELANE (0.97) | ELANEKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL23146904 | 0.81 | ELANE (0.58) | ELANEGAAKMT2AMEN1L3MBTL1 | |
| SCHEMBL7221645 | 0.81 | ELANE (0.58) | ELANEGAAKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214442-B | 3-substituted alpha-pyrone derivative as well as preparation method and application thereof | BIOLOGY INST SHANDONG ACAD SCI | 2014-09-10 | — | — | CN | claimed |
| US-9133155-B2 | Antibacterial agents: high-potency myxopyronin derivatives | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2015-09-15 | — | — | US | disclosed |
| US-9133155-B2 | Antibacterial agents: high-potency myxopyronin derivatives | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2015-09-15 | — | — | US | disclosed |
| CN-103360308-A | 1,4-dyhydroxy-6-methyl-2-pyridine ketone compound, and preparation method and use thereof | SUN WEIXIN | 2013-10-23 | — | — | CN | disclosed |
| US-20130237595-A1 | ANTIBACTERIAL AGENTS: HIGH-POTENCY MYXOPYRONIN DERIVATIVES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2013-09-12 | — | — | US | disclosed |
| US-20130237595-A1 | ANTIBACTERIAL AGENTS: HIGH-POTENCY MYXOPYRONIN DERIVATIVES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2013-09-12 | — | — | US | disclosed |
| WO-2012037508-A2 | ANTIBACTERIAL AGENTS: HIGH-POTENCY MYXOPYRONIN DERIVATIVES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-03-22 | — | — | WO | disclosed |
| US-7067523-B2 | Use of pyrone carboxylates for controlling pests | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-06-27 | — | — | US | disclosed |
| US-20050159479-A1 | Use of pyrone carboxylates for controlling pests | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-07-21 | — | — | US | disclosed |
| WO-2003099008-A1 | USE OF PYRONE CARBOXYLATES FOR CONTROLLING PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159479-A1 | Use of pyrone carboxylates for controlling pests | TET1, TET3, CNPY3 | ELANE 2080/4885GAA 4656/4885KMT2A 2113/4885 |
| US-20130237595-A1 | ANTIBACTERIAL AGENTS: HIGH-POTENCY MYXOPYRONIN DERIVATIVES | YBX1, POLRMT, YBX3 | ELANE 2782/4885GAA 893/4885KMT2A 2097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.