Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6027057 | 0.94 | ALDH1A1 (0.48) | ALDH1A1KDM4ETP53HPGDSMN1; SMN2 | |
| SCHEMBL6888848 | 0.93 | ALDH1A1 (0.52) | ALDH1A1KDM4ETP53HPGDSMN1; SMN2 | |
| SCHEMBL6887915 | 0.90 | CNR2 (0.46) | ALDH1A1KDM4ETP53HPGDSMN1; SMN2 | |
| SCHEMBL6888182 | 0.88 | ALDH1A1 (0.52) | ALDH1A1KDM4ETP53HPGDSMN1; SMN2 | |
| SCHEMBL13663138 | 0.79 | SMN1; SMN2 (0.51) | ALDH1A1KDM4ETP53HPGDSMN1; SMN2 | |
| SCHEMBL6887918 | 0.78 | SCN2A (0.45) | — | |
| SCHEMBL6887211 | 0.77 | TP53 (0.52) | ALDH1A1KDM4ETP53HPGDSMN1; SMN2 | |
| SCHEMBL5621233 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4ETP53HPGDSMN1; SMN2 | |
| SCHEMBL6027187 | 0.75 | PTPN1 (0.48) | ALDH1A1KDM4ETP53HPGDSMN1; SMN2 | |
| SCHEMBL6026686 | 0.75 | PTPN1 (0.48) | ALDH1A1KDM4ETP53HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613310-A1 | IMIDAZOLE DERIVATIVES FOR TREATMENT OF ALLERGIC AND HYPERPROLIFERATIVE DISORDERS | Avanir Pharmaceuticals (US) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004091610-A1 | IMIDAZOLE DERIVATIVES FOR TREATMENT OF ALLERGIC AND HYPERPROLIFERATIVE DISORDERS | AVANIR PHARMACEUTICALS (US) | 2004-10-28 | — | — | WO | disclosed |