SCHEMBL6027276

SCHEMBL6027276

CCOCC(OCC)OCCOC(=O)c1ccccc1C(=O)OCCOC(COCC)OCC

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.53
TSHR P16473 7/20 0.51
TDP1 Q9NUW8 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
CYP3A4 P08684 3/20 0.49
MAPK1 P28482 2/20 0.49
TP53 P04637 1/20 0.49
LMNA P02545 1/20 0.48
CA2 P00918 1/20 0.43
HSD17B10 Q99714 4/20 0.42
KDM4E B2RXH2 2/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
CDC25B P30305 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17798218 0.91 ALDH1A1 (0.56) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL17798228 0.87 TSHR (0.60) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL6027275 0.86 ALDH1A1 (0.50) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL3667884 0.83 TSHR (0.63) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL5962151 0.83 TSHR (0.63) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL6561284 0.81 ALDH1A1 (0.65) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL6561116 0.81 ALDH1A1 (0.65) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL6561262 0.81 ALDH1A1 (0.65) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL1189457 0.81 TSHR (0.60) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL5042423 0.80 ALDH1A1 (0.69) ALDH1A1TSHRTDP1L3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5466535-A Polyester material on surface with crosslinked adherent layer of acrylic resin and phthalate ester IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-11-14 US claimed
EP-0358181-A2 Polyvinyl chloride blends having improved physical properties The Geon Company (US) 1990-03-14 EP claimed
US-7101825-B2 Multilayer film DUPONT TEIJIM FILMS U.S. LIMITED PARTNERSHIP (US) 2006-09-05 US disclosed
US-20040147398-A1 Multilayer film DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP 2004-07-29 US disclosed
EP-1379393-B1 MULTILAYER FILM DUPONT TEIJIN FILMS US LTD (US) 2004-07-21 EP disclosed
EP-1379393-A1 MULTILAYER FILM Dupont Teijin Films U.S. Limited Partnership (US) 2004-01-14 EP disclosed
WO-2002081227-A1 MULTILAYER FILM DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2002-10-17 WO disclosed
US-5904976-A TRANSLUCENT POLYESTER LAYERS HAVING VARYING WIDE ANGLE HAZES, ACRYLIC RESIN LAYER; REUSABLE LABELS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1999-05-18 US disclosed
EP-0726847-B1 POLYMERIC FILM ICI PLC (GB) 1998-08-19 EP disclosed
EP-0576169-B1 Polymeric film ICI PLC (GB) 1997-03-12 EP disclosed
EP-0726847-A1 POLYMERIC FILM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1996-08-21 EP disclosed
US-5466535-A Polyester material on surface with crosslinked adherent layer of acrylic resin and phthalate ester IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-11-14 US disclosed
WO-1995012489-A1 POLYMERIC FILM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-05-11 WO disclosed
EP-0576169-A2 Polymeric film IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-12-29 EP disclosed
EP-0358181-A2 Polyvinyl chloride blends having improved physical properties The Geon Company (US) 1990-03-14 EP disclosed
US-3974080-A PHOSPHORIC ACID ESTER UNION CARBIDE CORPORATION (US) 1976-08-10 US disclosed