Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 6/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.33 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6027105 | 1.00 | KMT2A (0.38) | KMT2ASTING1PIK3CDGAATSHR | |
| SCHEMBL6464461 | 1.00 | KMT2A (0.38) | KMT2ASTING1PIK3CDGAATSHR | |
| SCHEMBL6467655 | 1.00 | KMT2A (0.38) | KMT2ASTING1PIK3CDGAATSHR | |
| SCHEMBL6026767 | 0.91 | KMT2A (0.45) | KMT2ASTING1PDE4DPDE4APDE4B | |
| SCHEMBL6026232 | 0.89 | STING1 (0.40) | KMT2ASTING1MTNR1AMTNR1BLMNA | |
| SCHEMBL4770361 | 0.88 | PIK3CD (0.47) | KMT2ASTING1PIK3CDGAATSHR | |
| SCHEMBL6025152 | 0.88 | KMT2A (0.47) | KMT2ASTING1PDE4DPDE4APDE4B | |
| SCHEMBL6026200 | 0.88 | KMT2A (0.47) | KMT2ASTING1PDE4DPDE4APDE4B | |
| SCHEMBL6026496 | 0.87 | PIK3CD (0.36) | KMT2ASTING1PIK3CDGAATSHR | |
| SCHEMBL6020509 | 0.85 | STING1 (0.42) | KMT2ASTING1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664037-A1 | HALO SUBSTITUTED BENZO [B] THIOPHENES WITH PI3K INHIBITORY ACTIVITY AS THERAPEUTIC AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005023800-A1 | HALO SUBSTITUTED BENZO`B! THIOPHENES WITH PI3K INHIBITORY ACTIVITY AS THERAPEUTIC AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-17 | — | — | WO | disclosed |